Article
A genome-wide search for linkage to renal function phenotypes in West Africans with type 2 diabetes.
American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Mar 2007
Chen Guanjie, Adeyemo Adebowale A, Zhou Jie, Chen Yuanxiu, Doumatey Ayo, Lashley Kerrie, Huang Hanxia, Amoah Albert, Agyenim-Boateng Kofi, Eghan Benjamin A, Okafor Godfrey, Acheampong Joseph, Oli Johnnie, Fasanmade Olufemi, Johnson Thomas, Rotimi Charles
Abstract excerpt
BACKGROUND: Reduced renal function often is a major consequence of diabetes and hypertension. Although several indices of renal function (eg, creatinine clearance) are clearly heritable and show linkage to several genomic regions, the specific underlying genetic determinants are still being sought. The purpose of this study is to conduct a genome-wide search for regions linked to 3 renal function phenotypes,...
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