Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Effect of the ubiquitous transcription factors, SP1 and MAZ, on NMDA receptor subunit type 1 (NR1) expression during neuronal differentiation.

Brain research. Molecular brain research - 15 Nov 2002

Okamoto Shu-ichi, Sherman Katerina, Bai Guang, Lipton Stuart A

Abstract excerpt

The silencer factor NRSF/REST has been reported to restrict expression to neurons of a variety of genes, including that encoding NMDA receptor subunit type 1 (NR1), by suppressing transcription in nonneuronal cells. However, we recently reported that in addition to the absence of NRSF/REST-bindin...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Brain
Share to GC Rich Sequence
Share to Neurons

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Phosphorylation

Share to Receptors, N-Methyl-D-Aspartate

Share to Sp1 Transcription Factor

Share to Synaptic Transmission

Share to Tumor Cells, Cultured

Source

Identifiers

PMID: 12425938
DOI: 10.1016/s0169-328x(02)00440-0

Genes

MAZ
REST

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12425938-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Effect of the ubiquitous transcription factors, SP1 and MAZ, on NMDA receptor subunit type 1 (NR1) expression during neuronal differentiation.PMID 12425938Read ↗

Absence of binding activity of neuron-restrictive silencer factor is necessary, but not sufficient for transcription of NMDA receptor subunit type 1 in neuronal cells.Semantic proximity Read ↗

NF-kappaB site interacts with Sp factors and up-regulates the NR1 promoter during neuronal differentiation.Semantic proximity Read ↗

Transcriptional repression by REST: recruitment of Sin3A and histone deacetylase to neuronal genes.Semantic proximity Read ↗

Repressor element-1 silencing transcription/neuron-restrictive silencer factor is required for neural sodium channel expression during development of Xenopus.Semantic proximity Read ↗

Transcriptional activation of REST by Sp1 in Huntington's disease models.Semantic proximity Read ↗

Transcriptional regulation of the neuropeptide VGF by the neuron-restrictive silencer factor/neuron-restrictive silencer element.Semantic proximity Read ↗

NRSF/REST is required in vivo for repression of multiple neuronal target genes during embryogenesis.Semantic proximity Read ↗

Silencer-mediated repression and non-mediated activation of BDNF and c-fos gene promoters in primary glial or neuronal cells.Semantic proximity Read ↗

Regulation of neural stem cell differentiation by transcription factors HNF4-1 and MAZ-1.Semantic proximity Read ↗

Synergy between the RE-1 Silencer of Transcription and NFκB in the Repression of the Neurotransmitter Gene TAC1 in Human Mesenchymal Stem CellsSemantic proximity Read ↗

Relaxation of glycine receptor and onconeural gene transcription control in NRSF deficient small cell lung cancer cell lines.Semantic proximity Read ↗

Transcription of genes encoding synaptic vesicle proteins in human neural stem cells: chromatin accessibility, histone methylation pattern, and the essential role of rest.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.