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Article

Molecular Analysis of Centrifugation Supernatant Fluid from Pancreaticobiliary Duct Samples Can Improve Cancer Detection

1 Jan 2012

Abstract excerpt

OBJECTIVE: We aimed to supplement microscopic examination of biliary cytobrush specimens to improve sensitivity by mutational profiling of: (1) selected cells microdissected from cytology slides and (2) corresponding cell-free DNA in residual supernatant fluid. STUDY DESIGN: From 43 patients with brushings of bile or pancreatic duct strictures, DNA was extracted from microdissected cells and 1-2 ml of...

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Share to Cholangiocarcinoma and Gallbladder Cancer Studies
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PMID: 22846349
DOI: 10.1159/000339638

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