Article
Soybean ascorbate peroxidase suppresses Bax-induced apoptosis in yeast by inhibiting oxygen radical generation.
Biochemical and biophysical research communications - 11 Jan 2002
Moon Haejeong, Baek Dongwon, Lee Boyoung, Prasad D Theertha, Lee Sang Yeol, Cho Moo Je, Lim Chae Oh, Choi Myung Suk, Bahk Jeongdong, Kim Myeong Ok, Hong Jong Chan, Yun Dae-Jin
Abstract excerpt
Bax, a mammalian proapoptotic member of the Bcl-2 family, can induce cell death when expressed in yeast or plant cells. To identify plant Bax inhibitors, we cotransformed a soybean cDNA library and the Bax gene into yeast cells and screened for expressed genes that prevented Bax-induced apoptosis...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
