Article
A trace amount of the human pro-apoptotic factor Bax induces bacterial death accompanied by damage of DNA.
The Journal of biological chemistry - 1 May 1998
Asoh S, Nishimaki K, Nanbu-Wakao R, Ohta S
Abstract excerpt
An amount of human pro-apoptotic Bax as low as 0.01% of total protein was sufficient to cause cell death in Escherichia coli. The bacterial cell death was examined using a viable bacteria-specific fluorescence indicator system and loss of colony formation ability. Co-expression of anti-apoptotic Bcl-xL showed a modest inhibitory effect on the cell death caused by Bax. The trace amount of Bax elongated E. coli and...
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