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Article

Accurate power approximations for chi2-tests in case-control association studies of complex disease genes.

Annals of human genetics - 1 Jul 2002

Jackson M R, Genin E, Knapp M, Escary J L

Abstract excerpt

A popular method for the analysis of case-control association studies is to compare the frequencies of the alleles between cases and controls by means of Pearson's chi2-statistic. Here, an approach for computing the power of this test is presented, which by computer simulation is shown to be more reliable than a previously published power approximation. Since the test based on Pearson's chi2- statistic can be...

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PMID: 12418971
DOI: 10.1017/S0003480002001203

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: pubmed, retrieved 5 Sept 2026.

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