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Article

Cochran-Armitage test versus logistic regression in the analysis of genetic association studies.

Human heredity - 1 Jan 2012

Wellek Stefan, Ziegler Andreas

Abstract excerpt

OBJECTIVE: The Cochran-Armitage trend test based on the linear regression model has become a standard procedure for association testing in case-control studies. In contrast, the logistic regression model is generally used for estimating effect sizes. The aim of this paper is to propose an approach that allows for association testing and parameter estimation by means of the same statistic. METHODS/RESULTS: The...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

Identifiers

PMID: 22212245
DOI: 10.1159/000334085

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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