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Article

Robust trend tests for genetic association using matched case-control design.

Statistics in medicine - 30 Sept 2006

Zheng Gang, Tian Xin

Abstract excerpt

Trend tests for genetic association using a matched case-control design are studied, which allows for a variable number of controls per case. However, the tests depend on the scores based on the underlying genetic model, thus it may result in substantial loss of power when the model is misspecified. Since the mode of inheritance may be unknown for complex diseases, robust trend tests in matched case-control...

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PMID: 16196079
DOI: 10.1002/sim.2278

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

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