Article
Oxysterol-binding protein (OSBP) is required for the perinuclear localization of intra-Golgi v-SNAREs.
Molecular biology of the cell - 1 Nov 2013
Nishimura Taki, Uchida Yasunori, Yachi Rieko, Kudlyk Tetyana, Lupashin Vladimir, Inoue Takao, Taguchi Tomohiko, Arai Hiroyuki
Abstract excerpt
Oxysterol-binding protein (OSBP) and OSBP-related proteins (ORPs) have been implicated in the distribution of sterols among intracellular organelles. OSBP regulates the Golgi cholesterol level, but how it relates to Golgi function is elusive. Here we report that OSBP is essential for the localization of intra-Golgi soluble vesicle N-ethylmaleimide-sensitive fusion attachment protein receptors (v-SNAREs)....
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