Article
A Rab1 mutant affecting guanine nucleotide exchange promotes disassembly of the Golgi apparatus.
The Journal of cell biology - 1 May 1994
Wilson B S, Nuoffer C, Meinkoth J L, McCaffery M, Feramisco J R, Balch W E, Farquhar M G
Abstract excerpt
The Golgi apparatus is a dynamic organelle whose structure is sensitive to vesicular traffic and to cell cycle control. We have examined the potential role for rab1a, a GTPase previously associated with ER to Golgi and intra-Golgi transport, in the formation and maintenance of Golgi structure. Bacterially expressed, recombinant rab1a protein was microinjected into rat embryonic fibroblasts, followed by analysis...
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