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Article

Trapping of misdirected dendritic cells in the granulomatous lesions of giant cell arteritis.

The American journal of pathology - 1 Nov 2002

Krupa Wei Ma, Dewan Misha, Jeon Myung-Shin, Kurtin Paul J, Younge Brian R, Goronzy Jörg J, Weyand Cornelia M

Abstract excerpt

Immature dendritic cells (DCs) are scattered throughout peripheral tissues and act as sentinels that sample the antigenic environment. After activation, they modify their chemokine receptor profile and migrate toward lymphoid tissues. On arrival, they have matured into chemokine-producing DCs that express co-stimulatory molecules and can prime naive T cells. Normal temporal arteries contain immature DCs that are...

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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Source

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Identifiers

PMID: 12414528
DOI: 10.1016/S0002-9440(10)64458-6
PMCID: PMC1850804

Genes

CCL19
CCL21
CCR7
CCL18

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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