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Aberrant phenotype of circulating antigen presenting cells in giant cell arteritis and polymyalgia rheumatica

2 Aug 2023

Abstract excerpt

Background: Giant Cell Arteritis (GCA) and Polymyalgia Rheumatica (PMR) are overlapping inflammatory diseases. Antigen-presenting cells (APCs), including monocytes and dendritic cells (DCs), are main contributors to the immunopathology of GCA and PMR. However, little is known about APC phenotypes in the peripheral blood at the time of GCA/PMR diagnosis. Methods: APCs among peripheral blood mononuclear cells...

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PMID: 37600779
DOI: 10.3389/fimmu.2023.1201575

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