Article
Dendritic cells in hyperplastic thymuses from patients with myasthenia gravis.
Muscle & nerve - 1 May 2003
Nagane Yuriko, Utsugisawa Kimiaki, Obara Daiji, Yamagata Munehisa, Tohgi Hideo
Abstract excerpt
To investigate the role of dendritic cells (DCs) in the hyperplastic myasthenia gravis (MG) thymus, we studied the frequency and distribution of three mature DC phenotypes (CD83(+)CD11c(+), CD86(+)CD11c(+), and HLA-DR(+)CD11c(+)) in samples from patients with MG whose symptoms dramatically improved following thymectomy and in non-MG control thymuses. In hyperplastic MG thymuses, mature DCs were much more numerous...
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