Article
[Pathophysiology of giant cell arteritis].
La Revue de medecine interne - 1 Jul 2013
Ly K-H, Liozon E, Fauchais A-L, Vidal E
Abstract excerpt
Giant cell arteritis is a large-vessel vasculitis affecting all three layers of the arterial wall. Histopathology of this vasculitis consists of an inflammatory infiltrate with CD4(+) T cells, macrophages, multinucleated giant cells, forming granulomas in the media. This infiltrate is associated with a destruction of the arterial wall, a fragmentation of the internal elastic lamina and a vascular remodeling...
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