Article
Difference in the expression of IL-9 and IL-17 correlates with different histological pattern of vascular wall injury in giant cell arteritis.
Rheumatology (Oxford, England) - 1 Sept 2015
Ciccia Francesco, Rizzo Aroldo, Guggino Giuliana, Cavazza Alberto, Alessandro Riccardo, Maugeri Rosario, Cannizzaro Alessandra, Boiardi Luigi, Iacopino Domenico Gerardo, Salvarani Carlo, Triolo Giovanni
Abstract excerpt
OBJECTIVE: GCA is a large- and medium-vessel arteritis characterized by a range of histological patterns of vascular wall injury. The aim of this study was to immunologically characterize the various histological patterns of GCA. METHODS: Thirty-five consecutive patients with biopsy-proven GCA and 15 normal controls were studied. IL-8, IL-9, IL-9R, IL-17, IL-4, TGF-β and thymic stromal lymphopoietin expression...
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