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Article

Fitness of in vitro selected Pseudomonas aeruginosa nalB and nfxB multidrug resistant mutants.

The Journal of antimicrobial chemotherapy - 1 Nov 2002

Sánchez Patricia, Linares Juan Francisco, Ruiz-Díez Beatriz, Campanario Ester, Navas Alfonso, Baquero Fernando, Martínez José L

Abstract excerpt

Overproduction of multidrug resistance (MDR) efflux pumps is involved in the resistance to a wide range of compounds in bacteria. These determinants extrude antibiotics, but also bacterial metabolites like quorum-sensing signals. Non-regulated extrusion of bacterial metabolites might produce a me...

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PMID: 12407121
DOI: 10.1093/jac/dkf185

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 5 Sept 2026. Prepared record publication-12407121-2026-09-05.1. Manifest publication-graph-cohort-2026-09-05.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 5 Sept 2026.

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