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The Impact of Antioxidant-Ciprofloxacin Combinations on the Evolution of Antibiotic Resistance in Pseudomonas aeruginosa Biofilms

2024-08-26

Abstract excerpt

<title>Abstract</title> <p>Antibiotic resistance in biofilms is a critical challenge driven by mechanisms such as increased oxidative stress, which could lead to enhanced mutagenesis. Experimental evolution studies have shown that biofilm growth fosters antimicrobial resistance and tolerance. The bactericidal antibiotic ciprofloxacin (CIP) exacerbates oxidative stress, enhancing reactive oxygen species (ROS) prod...

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Literature Corpus work
4b18a526-cda8-561d-b35c-216b917cf4ff
DOI
10.21203/rs.3.rs-4756544/v1
Open publication

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The Impact of Antioxidant-Ciprofloxacin Combinations on the Evolution of Antibiotic Resistance in Pseudomonas aeruginosa BiofilmsDOI 10.21203/rs.3.rs-4756544/v1
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