Article
Evidence that a novel quaternary compound and its organic N-chloramine derivative do not select for resistant mutants of Pseudomonas aeruginosa.
The Journal of hospital infection - 1 Sept 2015
De Silva M, Ning C, Ghanbar S, Zhanel G, Logsetty S, Liu S, Kumar A
Abstract excerpt
BACKGROUND: Pseudomonas aeruginosa is well known for causing hospital-acquired infections that are often difficult to treat because of its high intrinsic and acquired resistance to antibiotics. Resistance-nodulation-division (RND) efflux pumps are the major contributors to the intrinsic multidrug resistance (MDR) in this organism. Various biocides used in hospital settings have been shown to select for...
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