Article
Immunolocalization of PTCH protein in odontogenic cysts and tumors.
Journal of dental research - 1 Nov 2002
Barreto D C, Bale A E, De Marco L, Gomez R S
Abstract excerpt
The human patched gene (PTCH) functions in both embryologic development and tumor suppression. PTCH mutations have been found in odontogenic keratocysts. However, the expression and localization of the protein product of the gene have not been determined in odontogenic tumors and cysts. We investigated 68 odontogenic lesions by immunohistochemistry, and compared their PTCH expression with that in basal cell...
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