Article
1H magnetic resonance spectroscopy, cognitive function, and apolipoprotein E genotype in normal aging, mild cognitive impairment and Alzheimer's disease.
Journal of the International Neuropsychological Society : JINS - 1 Nov 2002
Kantarci Kejal, Smith Glenn E, Ivnik Robert J, Petersen Ronald C, Boeve Bradley F, Knopman David S, Tangalos Eric G, Jack Clifford R
Abstract excerpt
The aim of this study was to examine the associations of apolipoprotein E (APOE) genotype, metabolic changes in the posterior cingulate detected by 1H magnetic resonance spectroscopy (MRS), and neuropsychologic measures of memory and cognition both in normally aging elderly, and in patients with mild cognitive impairment (MCI) and AD. We studied 67 controls, 18 MCI and 33 AD patients. We used the Dementia Rating...
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