Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Decreased brain creatine levels in elderly apolipoprotein E epsilon 4 carriers.

Journal of neural transmission (Vienna, Austria : 1996) - 1 Mar 2003

Laakso M P, Hiltunen Y, Könönen M, Kivipelto M, Koivisto A, Hallikainen M, Soininen H

Abstract excerpt

Apolipoprotein E (ApoE) genotype has been shown to influence results in neuroimaging studies using a number of various imaging modalities. No in vivo data exists on whether or not there are ApoE-related changes observable by proton magnetic resonance spectroscopy (MRS). In this study we measured...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Analysis of Variance
Share to Apolipoprotein E4
Share to Apolipoproteins E

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Chi-Square Distribution

Share to Creatine

Share to Magnetic Resonance Spectroscopy

Share to Mental Status Schedule

Source

Identifiers

PMID: 12658375
DOI: 10.1007/s00702-002-0783-7

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 4 Sept 2026. Prepared record publication-12658375-2026-09-04.2. Manifest publication-graph-cohort-2026-09-04.2.

Source receipt: PubMed via Helena Literature Corpus, retrieved 4 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Decreased brain creatine levels in elderly apolipoprotein E epsilon 4 carriers.PMID 12658375Read ↗

APOE genotype modulates proton magnetic resonance spectroscopy metabolites in the aging brain.Semantic proximity Read ↗

Imaging studies and APOE genotype in persons at risk for Alzheimer's disease.Semantic proximity Read ↗

Lower levels of N-acetylaspartate in multiple sclerosis patients with the apolipoprotein E epsilon4 allele.Semantic proximity Read ↗

Distinct patterns of brain activity in young carriers of the APOE-epsilon4 allele.Semantic proximity Read ↗

Reduced functional brain activity response in cognitively intact apolipoprotein E epsilon4 carriers.Semantic proximity Read ↗

Effects of sex and APOE ε4 genotype on brain mitochondrial high-energy phosphates in midlife individuals at risk for Alzheimer's disease: A 31Phosphorus MR spectroscopy study.Semantic proximity Read ↗

APOE related alterations in cerebral activation even at college age.Semantic proximity Read ↗

Evidence for distinct neuro-metabolic phenotypes in humans.Semantic proximity Read ↗

No difference in cerebral glucose metabolism in patients with Alzheimer disease and differing apolipoprotein E genotypes.Semantic proximity Read ↗

MRI of carriers of the apolipoprotein E e4 allele-evidence for structural differences in normal-appearing brain tissue in e4+ relative to e4- young adults.Semantic proximity Read ↗

Cognitive ERPs are related to ApoE allelic variation in mildly cognitively impaired patients.Semantic proximity Read ↗

APOE-epsilon4 is not associated with cognitive impairment in relapsing-remitting multiple sclerosis.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.