Article
The ASH1 HOMOLOG 2 (ASHH2) histone H3 methyltransferase is required for ovule and anther development in Arabidopsis.
PloS one - 12 Nov 2009
Grini Paul E, Thorstensen Tage, Alm Vibeke, Vizcay-Barrena Gema, Windju Susanne S, Jørstad Tommy S, Wilson Zoe A, Aalen Reidunn B
Abstract excerpt
BACKGROUND: SET-domain proteins are histone lysine (K) methyltransferases (HMTase) implicated in defining transcriptionally permissive or repressive chromatin. The Arabidopsis ASH1 HOMOLOG 2 (ASHH2) protein (also called SDG8, EFS and CCR1) has been suggested to methylate H3K4 and/or H3K36 and is similar to Drosophila ASH1, a positive maintainer of gene expression, and yeast Set2, a H3K36 HMTase. Mutation of the...
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