Article
Histone H2A.Z and DNA methylation are mutually antagonistic chromatin marks.
Nature - 6 Nov 2008
Zilberman Daniel, Coleman-Derr Devin, Ballinger Tracy, Henikoff Steven
Abstract excerpt
Eukaryotic chromatin is separated into functional domains differentiated by post-translational histone modifications, histone variants and DNA methylation. Methylation is associated with repression of transcriptional initiation in plants and animals, and is frequently found in transposable elements. Proper methylation patterns are crucial for eukaryotic development, and aberrant methylation-induced silencing of...
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