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Article

Abolition of hypertension-induced end-organ damage by androgen receptor blockade in transgenic rats harboring the mouse ren-2 gene.

Journal of the American Society of Nephrology : JASN - 1 Nov 2002

Baltatu Ovidiu, Cayla Cécile, Iliescu Radu, Andreev Dmitrii, Jordan Cynthia, Bader Michael

Abstract excerpt

A sexual dimorphism in hypertension has been observed in both human and laboratory animal studies. The mechanisms by which male sex hormones regulate cardiovascular homeostasis are still not yet fully understood and represent the subject of this study. The possible involvement of androgen receptors in the development of hypertension and end-organ damage in transgenic rats harboring the mouse Ren-2 renin gene...

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PMID: 12397037
DOI: 10.1097/01.asn.0000033327.65390.ca

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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