Article
Cytokine polymorphisms in patients with pemphigus.
Archives of dermatological research - 1 Jan 2005
Eberhard Yanina, Burgos Elisa, Gagliardi Julio, Vullo Carlos Maria, Borosky Alicia, Pesoa Susana, Serra Horacio Marcelo
Abstract excerpt
The aim of this study was to assess whether tumor necrosis factor alpha (TNF-alpha), transforming growth factor beta1 (TGF-beta1) and interleukin-10 (IL-10) polymorphisms are among the factors influencing the development of pemphigus. Whole blood from 20 patients with pemphigus and 24 control subjects was taken. Genomic DNA was obtained and cytokine genotyping for IL-10 (-1082 G/A; -819 C/T), TGFB1 (codon 10 C/T,...
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