Article
The zebrafish mutant gene chardonnay (cdy) encodes divalent metal transporter 1 (DMT1).
Blood - 15 Dec 2002
Donovan Adriana, Brownlie Alison, Dorschner Michael O, Zhou Yi, Pratt Stephen J, Paw Barry H, Phillips Ruth B, Thisse Christine, Thisse Bernard, Zon Leonard I
Abstract excerpt
Iron is an essential nutrient required for the function of all cells, most notably for the production of hemoglobin in red blood cells. Defects in the mechanisms of iron absorption, storage, or utilization can lead to disorders of iron-limited erythropoiesis or iron overload. In an effort to further understand these processes, we have used the zebrafish as a genetic system to study vertebrate iron metabolism....
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