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Zebrafish model of <i>tcn2</i> deletion reveals new molecular insights into the role of vitamin B12 in embryonic development

2023-10-18

Abstract excerpt

Vitamin B12 (B12) is one of the key co-factors in One-Carbon Metabolism pathway, and its dysregulation is associated with various clinical conditions including congenital malformations, neural tube defects, and low birthweight, etc. However, the underlying molecular mechanism is scarcely studied. This study investigated the role of B12 in early embryonic development by generating a knockout of transcobalamin 2 (...

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Literature Corpus work
f5df79e3-69b1-5ab8-8068-534b05d02d61
DOI
10.1101/2023.10.14.562325
Open publication

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Zebrafish model of <i>tcn2</i> deletion reveals new molecular insights into the role of vitamin B12 in embryonic developmentDOI 10.1101/2023.10.14.562325
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