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Article

Mutation in the abcb7 gene causes abnormal iron and fatty acid metabolism in developing medaka fish.

Development, growth & differentiation - 1 Dec 2008

Miyake Akimitsu, Higashijima Shin-ichi, Kobayashi Daisuke, Narita Takanori, Jindo Tomoko, Setiamarga Davin H E, Ohisa Satoshi, Orihara Nobuaki, Hibiya Kenta, Konno Sayaka, Sakaguchi Sae, Horie Kyohei, Imai Yoshiyuki, Naruse Kiyoshi, Kudo Akira, Takeda Hiroyuki

Abstract excerpt

The medaka fish (Oryzias latipes) is an emerging model organism for which a variety of unique developmental mutants have now been generated. Our recent mutagenesis screening of the medaka isolated a unique mutant that develops a fatty liver at larval stages. Positional cloning identified the responsible gene as medaka abcb7. Abcb7, a mitochondrial ABC (ATP binding cassette) half-transporter, has been implicated...

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Identifiers

PMID: 19046159
DOI: 10.1111/j.1440-169X.2008.01068.x

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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