Article
Killer Ig-like receptor haplotype analysis by gene content: evidence for genomic diversity with a minimum of six basic framework haplotypes, each with multiple subsets.
Journal of immunology (Baltimore, Md. : 1950) - 1 Nov 2002
Hsu Katharine C, Liu Xiao-Rong, Selvakumar Annamalai, Mickelson Eric, O'Reilly Richard J, Dupont Bo
Abstract excerpt
Killer Ig-like receptor (KIR) genes constitute a multigene family whose genomic diversity is achieved through differences in gene content and allelic polymorphism. KIR haplotypes containing a single activating KIR gene (A-haplotypes), and KIR haplotypes with multiple activating receptor genes (B-haplotypes) have been described. We report the evaluation of KIR gene content in extended families, sibling pairs, and...
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