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Article

Fatal immunopathogenesis by SIV/HIV-1 (SHIV) containing a variant form of the HIV-1SF33 env gene in juvenile and newborn rhesus macaques.

Virology - 10 Oct 1999

Luciw P A, Mandell C P, Himathongkham S, Li J, Low T A, Schmidt K A, Shaw K E, Cheng-Mayer C

Abstract excerpt

SIV/HIV-1 (SHIV) chimeric clones, constructed by substituting portions of the pathogenic molecular clone SIVmac239 with counterpart portions from HIV-1 clones, provide a means to analyze functions of selected HIV-1 genes in vivo in nonhuman primates. Our studies focused on SHIVSF33, which contains the vpu, tat, rev, and env genes of the cytopathic, T-cell line tropic clone HIV-1sf33 (subtype-B); this clone has a...

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Share to Acquired Immunodeficiency Syndrome
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Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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Share to Genes, env

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Share to Simian Acquired Immunodeficiency Syndrome

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Source

Identifiers

PMID: 10544087
DOI: 10.1006/viro.1999.9908

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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