Article
Direct modulatory effect of C-reactive protein on primary human monocyte adhesion to human endothelial cells.
Clinical and experimental immunology - 1 Nov 2002
Woollard K J, Phillips D C, Griffiths H R
Abstract excerpt
C-reactive protein (CRP) is the prototypic acute phase serum protein in humans. The effects of CRP on primary human monocyte adhesion molecule expression and interaction with the endothelium have not been studied. Herein, we describe an investigation into the phenotypic and functional consequences of CRP binding to peripheral blood monocytes ex vivo. Peripheral whole blood was collected from healthy, non-smoking...
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