Article
Exercise training attenuates coronary smooth muscle phenotypic modulation and nuclear Ca2+ signaling.
American journal of physiology. Heart and circulatory physiology - 1 Dec 2002
Wamhoff B R, Bowles D K, Dietz N J, Hu Q, Sturek M
Abstract excerpt
Physical inactivity is an independent risk factor for coronary heart disease, yet the mechanism(s) of exercise-related cardioprotection remains unknown. We tested the hypothesis that coronary smooth muscle after exercise training would have decreased mitogen-induced phenotypic modulation and enhanced regulation of nuclear Ca(2+). Yucatan swine were endurance exercise trained (EX) on a treadmill for 16-20 wk. EX...
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