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Article

Impaired function of coronary BK(Ca) channels in metabolic syndrome.

American journal of physiology. Heart and circulatory physiology - 1 Nov 2009

Borbouse Léna, Dick Gregory M, Asano Shinichi, Bender Shawn B, Dincer U Deniz, Payne Gregory A, Neeb Zachary P, Bratz Ian N, Sturek Michael, Tune Johnathan D

Abstract excerpt

The role of large-conductance Ca(2+)-activated K(+) (BK(Ca)) channels in regulation of coronary microvascular function is widely appreciated, but molecular and functional changes underlying the deleterious influence of metabolic syndrome (MetS) have not been determined. Male Ossabaw miniature swine consumed for 3-6 mo a normal diet (11% kcal from fat) or an excess-calorie atherogenic diet that induces MetS (45%...

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Identifiers

PMID: 19749164
DOI: 10.1152/ajpheart.00466.2009
PMCID: PMC2781383

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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