Article
Biphasic alterations in coronary smooth muscle Ca(2+) regulation in a repeat cross-sectional study of coronary artery disease severity in metabolic syndrome.
Atherosclerosis - 1 Jun 2016
McKenney-Drake Mikaela L, Rodenbeck Stacey D, Owen Meredith K, Schultz Kyle A, Alloosh Mouhamad, Tune Johnathan D, Sturek Michael
Abstract excerpt
BACKGROUND AND AIMS: Coronary artery disease (CAD) is progressive, classified by stages of severity. Alterations in Ca(2+) regulation within coronary smooth muscle (CSM) cells in metabolic syndrome (MetS) have been observed, but there is a lack of data in relatively early (mild) and late (severe) stages of CAD. The current study examined alterations in CSM Ca(2+) regulation at several time points during CAD...
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