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Article

Sequence variants in the human 25-hydroxyvitamin D3 1-alpha-hydroxylase (CYP27B1) gene are not associated with prostate cancer risk.

The Prostate - 1 Nov 2002

Hawkins Gregory A, Cramer Scott D, Zheng Siqun L, Isaacs Sarah D, Wiley Kathy E, Chang Bao-Li, Bleecker Eugene R, Walsh Patrick C, Meyers Deborah A, Isaacs William B, Xu Jianfeng

Abstract excerpt

BACKGROUND: 1,25-dihydroxyvitamin D(3) has been shown to have antiproliferative properties on normal and neoplastic prostatic cells. 25-hydroxyvitamin D(3) 1-alpha-hydroxylase, the enzyme that catalyzes the final step of vitamin D synthesis, converting 25-hydroxyvitamin D(3) to 1,25-dihydroxyvitamin D(3), is expressed in the prostate. METHODS: The human 25-hydroxyvitamin D(3) 1-alpha-hydroxylase gene (CYP27B1)...

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PMID: 12386916
DOI: 10.1002/pros.10144

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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