Article
The CYP3A4 *1B polymorphism and prostate cancer susceptibility in a Portuguese population.
Cancer genetics and cytogenetics - 1 Sept 2007
Nogal Ana, Coelho Ana, Catarino Raquel, Morais António, Lobo Francisco, Medeiros Rui
Abstract excerpt
Testosterone exposure has been implicated in prostate carcinogenesis, and genes that alter its metabolism, such as CYP3A4, have been associated with prostate cancer susceptibility. The aim of our study was to assess the relationship between the CYP3A4 *1B polymorphism and its possible role in the...
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