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Single Nucleotide Polymorphisms in 25-Hydroxyvitamin D3 1-Alpha-Hydroxylase (CYP27B1) Gene: The Risk of Malignant Tumors and Other Chronic Diseases.

Nutrients - 18 Mar 2020

Latacz Maria, Snarska Jadwiga, Kostyra Elżbieta, Fiedorowicz Ewa, Savelkoul Huub Fj, Grzybowski Roman, Cieślińska Anna

Abstract excerpt

: Vitamin D is widely known for its roles in the promotion of apoptosis and differentiation, with simultaneous inhibition of proliferation, inflammation, angiogenesis, invasion, and metastasis. Modern literature lacks complete information on polymorphisms in CYP27B1, the only enzyme capable of vitamin D activation. This review presents gathered data that relate to genetic variants in CYP27B1 gene in correlation...

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Identifiers

PMID: 32197412
DOI: 10.3390/nu12030801
PMCID: PMC7146376

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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