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Article

Significance of early phenotypic change of glomerular podocytes detected by Pax2 in primary focal segmental glomerulosclerosis.

American journal of kidney diseases : the official journal of the National Kidney Foundation - 1 Mar 2002

Ohtaka Akihiko, Ootaka Tetsuya, Sato Hiroshi, Soma Jun, Sato Toshinobu, Saito Takao, Ito Sadayoshi

Abstract excerpt

In primary focal segmental glomerulosclerosis (FSGS), phenotypic alteration of podocytes is important for the development of cellular lesions (CLs), which precede glomerular scar formation. WT1 and Pax2 are transcription factors involved in kidney development and phenotypic regulation of glomerular epithelial cells. However, the role of WT1 and Pax2 in the development of CLs in primary FSGS is unclear. Using...

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Identifiers

PMID: 11877566
DOI: 10.1053/ajkd.2002.31391

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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