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Article

Genome-wide allelotyping of a new in vitro model system reveals early events in breast cancer progression.

Cancer research - 15 Oct 2002

Li Zheng, Meng Zhen Hang, Sayeed Aejaz, Shalaby Refaat, Ljung Britt-Marie, Dairkee Shanaz H

Abstract excerpt

Toward the goal of identifying early genetic losses, which mediate the release of human breast epithelium from replicative suppression leading to cellular immortalization, we have used a newly developed in vitro model system. This system consists of epithelial cultures derived from noncancerous breast tissue, treated with the chemical carcinogen N-ethyl-N-nitrosourea, and continuously passaged to yield cell...

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PMID: 12384566

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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