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Article

Neural stem cell heterogeneity demonstrated by molecular phenotyping of clonal neurospheres.

Proceedings of the National Academy of Sciences of the United States of America - 29 Oct 2002

Suslov Oleg N, Kukekov Valery G, Ignatova Tatyana N, Steindler Dennis A

Abstract excerpt

Neural stem cells (NSCs) in vitro are able to generate clonal structures, "neurospheres," that exhibit intra-clonal neural cell-lineage diversity; i.e., they contain, in addition to NSCs, neuronal and glial progenitors in different states of differentiation. The present study focuses on a subset of neurospheres derived from fresh clinical specimens of human brain by using an in vitro system that relies on...

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Identifiers

PMID: 12381788
DOI: 10.1073/pnas.212525299
PMCID: PMC137913

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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