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Human cortical glial tumors contain neural stem‐like cells expressing astroglial and neuronal markers in vitro

11 Jun 2002

Abstract excerpt

Neural stem cells from neurogenic regions of mammalian CNS are clonogenic in an in vitro culture system exploiting serum and anchorage withdrawal in medium supplemented with methyl cellulose and the pleiotropic growth factors EGF, FGF2, and insulin. The aim of this study was to test whether cortical glial tumors contain stem-like cells capable, under this culture system, of forming clones showing intraclonal...

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PMID: 12203386
DOI: 10.1002/glia.10094

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