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Article

No mutations of the Bub1 gene in human gastric and oral cancer cell lines.

Oncology reports - 1 Jan 2000

Nakagawa Hiroyuki, Yokozaki Hiroshi, Oue Naohide, Sugiyama Masaru, Ishikawa Takenori, Tahara Eiichi, Yasui Wataru

Abstract excerpt

Chromosomal instability is one of the most important characteristics underlying tumorigenesis. Certain colorectal cancers with chromosomal instability have been shown to have inactivation of a spindle assembly checkpoint party due to mutation of Bub1, a mitotic checkpoint gene. We performed sequencing analysis on reverse transcriptase-polymerase chain reaction (RT-PCR) product of the Bub1 cDNA (entire coding...

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PMID: 12375025

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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No mutations of the Bub1 gene in human gastric and oral cancer cell lines.PMID 12375025Read ↗

No mutations of the Bub1 gene in human gastric carcinomas.Semantic proximity Read ↗

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Genomic instability at the BUB1 locus in colorectal cancer, but not in non-small cell lung cancer.Semantic proximity Read ↗

Frequent mutations of human Mad2, but not Bub1, in gastric cancers cause defective mitotic spindle checkpoint.Semantic proximity Read ↗

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Prevalence of germline mutations in the spindle assembly checkpoint gene BUB1B in individuals with early-onset colorectal cancer.Semantic proximity Read ↗

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