Article
K-ras mutation, p53 overexpression, and microsatellite instability in biliary tract cancers: a population-based study in China.
Clinical cancer research : an official journal of the American Association for Cancer Research - 1 Oct 2002
Rashid Asif, Ueki Takashi, Gao Yu-Tang, Houlihan Patrick Scott, Wallace Charita, Wang Bing-Sheng, Shen Ming-Chang, Deng Jie, Hsing Ann W
Abstract excerpt
PURPOSE: The genetic alterations in biliary tract cancer and clinicopathological associations have not been studied in large population-based studies. EXPERIMENTAL DESIGN: We evaluated genetic alterations such as K-ras mutation, p53 overexpression, microsatellite instability (MSI), and alterations of the polyadenine tract present in the transforming growth factor beta receptor type II (TGFbetaRII) gene in 126...
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