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Low prevalence of biliary tract cancer with defective mismatch repair genes in a Japanese hospital‑based population

4 Nov 2021

Abstract excerpt

Recent studies have reported that immune checkpoint inhibitors are effective against various defective mismatch repair (dMMR)/microsatellite instability-high (MSI-H) cancers. A limited number of reports are available on the frequency of dMMR/MSI-H carcinoma in biliary tract cancer (BTC), describing its clinicopathological characteristics and prognosis. The latter carcinoma is also associated with Lynch syndrome...

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PMID: 34820003
DOI: 10.3892/ol.2021.13122

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