Article
Defining the boundaries of the testis angiotensin I-converting enzyme ectodomain.
Biochemical and biophysical research communications - 11 Oct 2002
Chubb Anthony J, Schwager Sylva L U, Woodman Zenda L, Ehlers Mario R W, Sturrock Edward D
Abstract excerpt
Numerous cytokines, receptors, and ectoenzymes, including angiotensin I-converting enzyme (ACE), are shed from the cell surface by limited proteolysis at the juxtamembrane stalk region. The membrane-proximal C domain of ACE has been implicated in sheddase-substrate recognition. We mapped the func...
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