Article
Quantitative determination of Fcgamma receptor genes by means of fluorescence-based real-time polymerase chain reaction.
Tissue antigens - 1 Jul 2002
Gittinger F S, Schindler-Wuepper L, Kissel K, Bux J
Abstract excerpt
The granulocyte antigens HNA-1a, -1b and -1c reside on the FcgammaIIIb receptor, which is exclusively expressed on neutrophils. They are involved in autoimmune and alloimmune neutropenias as well as in severe transfusion reactions. Recent family studies show the HNA-1c antigen to be inheritably linked to HNA-1a, resulting in individuals carrying three genes. Using sequence-specific primers, the HNA antigens can...
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