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Article

Development of a facile fluorescent assay for the detection of 80 mutations within the p53 gene.

Molecular medicine (Cambridge, Mass.) - 1 May 2002

Hodgson Darren R, Foy Carole A, Partridge Maxine, Pateromichelakis Stelios, Gibson Neil J

Abstract excerpt

BACKGROUND: Alterations in the p53 tumor suppressor gene constitute one of the most frequent genetic events associated with the development of human cancers. Determination of an individual's p53 status may be of value in early diagnosis, prediction of response to treatment, and for the detection of minimal residual cancer. Recent studies have also revealed that specific mutations affecting the p53 gene are...

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PMID: 12359953
PMCID: PMC2039988

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-07.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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