Article
Changes in AMPA receptor binding in an animal model of inborn paroxysmal dystonia.
Experimental neurology - 1 Aug 2002
Nobrega J N, Raymond R, Barlow K, Hamann M, Richter A
Abstract excerpt
Previous pharmacological studies suggested that glutamatergic overactivity contributes to manifestation of dystonic attacks in mutant hamsters (dt(sz)), a model of idiopathic paroxysmal dystonia in which episodes of dystonia occur in response to stress. In the present study, [(3)H]AMPA (alpha-amino-3-hydroxy-5-methylisoxazole-4-propionate) receptor binding was determined by autoradiographic analyses in 41 brain...
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