Article
Retinoblastoma-cyclin-dependent kinase pathway deregulation in vestibular schwannomas.
The Laryngoscope - 1 Sept 2002
Lasak John M, Welling D Bradley, Akhmametyeva Elena M, Salloum Mariah, Chang Long-Sheng
Abstract excerpt
OBJECTIVES: The purpose of the study was to identify genes of the retinoblastoma protein (pRb)-cyclin-dependent kinase (CDK) pathway that are deregulated in vestibular schwannomas when compared with normal vestibular nerve tissues. STUDY DESIGN: Expression profiles in eight vestibular schwannomas (four sporadic tumors, one neurofibromatosis type 2 tumor, and three cystic tumors) and a paired normal vestibular...
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