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Article

Deregulated Genes in Sporadic Vestibular Schwannomas

16 Jan 2010

Abstract excerpt

OBJECTIVE: In search of genes associated with vestibular schwannoma tumorigenesis, this study examines the gene expression in human vestibular nerve versus vestibular schwannoma tissue samples using microarray technology. MATERIAL AND METHODS: RNA was extracted from 3 vestibular nerves (serving as control) and 16 solid, sporadic vestibular schwannomas. RNA (5 microg) was used in the labeling and biotinylation...

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PMID: 19816230
DOI: 10.1097/mao.0b013e3181be6478

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